Exhausted T cell signature predicts immunotherapy response in ER-positive breast cancer
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چکیده
منابع مشابه
An ER-associated miRNA signature predicts prognosis in ER-positive breast cancer
BACKGROUND Breast cancer patients with positive estrogen receptor (ER) have a better prognosis. However, no prognostic miRNA signature was reported in the ER-positive breast cancer. The aim of the study was to identify and assess the prognostic significance of a miRNA signature in ER-positive breast cancer. METHODS Two cohorts from The Cancer Genome Atlas (TCGA) dataset were used as training ...
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Breast cancer patients have different responses to chemotherapeutic treatments. Genes associated with drug response can provide insight to understand the mechanisms of drug resistance, identify promising therapeutic opportunities, and facilitate personalized treatment. Estrogen receptor (ER) positive and ER negative breast cancer have distinct clinical behavior and molecular properties. However...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2020
ISSN: 2041-1723
DOI: 10.1038/s41467-020-17414-y